2012年7月16日 星期一

Separate lives_Phill Collins


You called me from the room in your hotel
All full of romance for someone that you met
And telling me how sorry you were, leaving so soon
And that you miss me sometimes when you're alone in your room
Do I feel lonely too?
You have no right to ask me how I feel
You have no right to speak to me so kind
We can't go on just holding on to time
Now that we're living separate lives
Well I held on to let you go
And if you lost your love for me, well you never let it show
There was no way to compromise
So now we're living (living)
Separate livesOoh, it's so typical, love leads to isolation
So you build that wall (build that wall)
Yes, you build that wall (build that wall)
And you make it stronger
Well you have no right to ask me how I feel
You have no right to speak to me so kind
Some day I might (I might) find myself looking in your eyes
But for now, we'll go on living separate lives
Yes for now, we'll go on living separate lives
Separate lives


From:http://www.youtube.com/watch?v=Q_4w3-CPP6E

2012年7月11日 星期三

Can spending less time sitting down add years to life?By Michelle Roberts ,Health editor, BBC News online

Limiting the time we spend sitting to just three hours a day could add an extra two years to our life expectancy, scientists calculate.



             The analysis assumes a causal association rather than proving that there is one

Similarly, if we cut daily TV viewing down to two hours we could add on 1.4 years, they say in a report for the online journal BMJ Open. But experts say the US estimates, which are based on five separate population studies, are too unreliable to predict personal risk.
Plus the targets are unfeasible.
Prof David Spiegelhalter, an expert in risk calculations at the University of Cambridge, said: "This is a study of populations, and does not tell you personally what the effect of getting off the sofa might be. "It seems plausible that if future generations moved around a bit more, then they might live longer on average. "But very few of us currently spend less than three hours sitting each day, and so this seems a very optimistic target."
Sitting comfortably?
Adults are advised to do at least two-and-a-half hours of moderate-intensity aerobic activity such as cycling or fast walking every week, as well as a couple of sessions of muscle-strengthening exercises like lifting weights or digging in the garden.
But even if you do this recommended amount, you may still be sedentary - for example, if you work in an office you may spend most of your working day sitting.
A growing body of evidence suggests the more time we spend sitting, the less healthy we may be.Several studies have linked sitting and television viewing to conditions like diabetes and heart disease as well as an increased overall risk of death. But finding a link is not the same as proving one thing actually causes the other. And although this latest piece of research does not claim to be proof, the researchers themselves acknowledge there are flaws that make its findings less than reliable.
The work looked at a large sample of people - almost 167,000 in total - but did not scrutinise the different lifestyles these individuals led.It is not clear how many of these people were less healthy to begin with and who, therefore, might spend more time sitting down as a result. And the studies relied on the participants accurately recalling and reporting how much time they spent lounging around. Dr Peter Katzmarzyk and Prof I-Min Lee who carried out the review stress that their estimates are theoretical.
But given that the adults in their research spent, on average, half of their days sitting "engaged in sedentary pursuits", the findings could provide an important public health warning.

Natasha Stewart, senior cardiac nurse at the British Heart Foundation, said: "This research only suggests a causal association between sedentary behaviour and a shorter life expectancy. It also used American data so we'd need to see more research to understand what it means for the UK population."However, it does highlight what we already know about sedentary behaviour being a risk factor for developing heart disease. And recent UK guidelines suggested we should all minimise the time we spend sitting down.
"We all need to be regularly active to keep our hearts healthy. So whether it's by walking to the local shop rather than driving, or playing sport rather than watching it on TV, there are lots of ways to be more active and improve your health."


From:http://www.bbc.co.uk/news/health-18767278










2012年7月10日 星期二

Gene flaw 'explains why drugs failed to treat MS'


Scientists have identified why a once-promising class of drugs do not help people with multiple sclerosis.
An Oxford University team say a genetic variant linked to MS means the drugs which work for patients with other autoimmune diseases will not work for them.The team, writing in Nature, say the drugs can actually make symptoms worse.Experts say the work shows how a person's genetic make-up could affect how they responded to treatment.The drugs, called anti-TNFs, work for patients with rheumatoid arthritis and inflammatory bowel disease, but they have not done so for patients with MS and researchers were unsure why.
Mimicking
The Oxford University team looked at one particular genetic variant, found in a gene called TNFRSF1A, which has previously been associated with the risk of developing MS.

The normal, long version of the protein sits on the surface of cells and binds the TNF signalling molecule, which is important for a number of processes in the body.But the team discovered the variant caused the production of an altered, shortened version which "mops up" TNF, preventing it from triggering signals - essentially the same thing that TNF blocking drugs do.
This explains why a study 10 years ago found the drugs make MS patients significantly worse and exacerbate the disease, the researchers suggest.
Professor Lars Fugger of the Nuffield Department of Clinical Neurosciences, who led the work, said: "The hope has been that analyses of the whole human genome would lead to findings that are clinically relevant.
"We show that this is possible. It's one of the first such examples, certainly in autoimmune disease."
He added: 'Whilst the TNFRSF1A gene variant is linked to a modest risk of developing MS, the drug that mimics the effect of the variant has a considerably greater impact.
"The effects of genetic variants influencing disease risk or resistance can be amplified by drugs. This has often been completely overlooked, but will be critical for using genetic findings in a medical context."
Nick Rijke, director of policy and research at the MS Society, said: "There are many genes associated with MS, but we know little about the role they play or the influence they have on the condition.
"This important study has shown that some of your genes can play a part in deciding whether or not you respond to a treatment.
"In the future this could help ensure that people with MS are offered the drug treatments that are most likely to work for them."


FROM:http://www.bbc.co.uk/news/health-18738785





2012年7月6日 星期五

In The Shadow Of A Badge/A Spiritual Memoir




Lillie's Story: After more than nine years and as a result of her personal experiences at the Flight 93 crash site in Shanksville (PA), Lillie recently completed a 200-page book detailing a deeply spiritual event that took place at the site on 9-11. Entitled In The Shadow Of A Badge
A Spiritual Memoir, the book reflects her story about the visitation of Angels during the first hours at the crash site.
It is a narrative non-fiction, first-hand account of the spiritual experience Lillie encountered while serving in her professional capacity as the Community Affairs Coordinator with the FBI (Pittsburgh Division). What she saw and/or heard is a personal interpretation of the events leading up to and following 9-11 and, in particular, the Flight 93 crash. The book also details her ongoing journey of personal healing and recovery from Post Traumatic Stress Disorder (PTSD) following her experiences that day.


From:http://www.youtube.com/watch?v=X98TTuIpbbU